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You are here:Home » Antibodies » Abs to Enzymes, Cytochrome » Anti -Cytochrome p450 2C9 (CYP2C9, (R)(S)-limonene 6-monooxygenase, (S)-limonene 6-monooxygenase, Cytochrome P450 PB-1, Cytochrome P450 MP-4, Cytochrome P450 MP-8, S-mephenytoin 4-hydroxylase)

Anti -Cytochrome p450 2C9 (CYP2C9, (R)(S)-limonene 6-monooxygenase, (S)-limonene
6-monooxygenase, Cytochrome P450 PB-1, Cytochrome P450 MP-4, Cytochrome P450 MP-8,
S-mephenytoin 4-hydroxylase)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum B N
P450 enzymes are divided into two groups: steroidogenic and xenobiotic. The latter group is comprised of three families 1, 2 and 3. The xenobiotic p450's are involved in most oxidative drug metabolism. Work in this area is ongoing but studies suggest that all known drug metabolism is mediated by family members: CYP3A, CYP2D6, CYP1A2, CYP2C9/10, CYP2C19 and CYP2E1. The product is a neutralizing antibody which is a potent inhibitor of CYP2C9 activity. Inhibition of CYP2C19 activity has also been observed.
Catalog #C9095-15H
ApplicationsSuitable for use in Western Blot and Functional assays. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1:5000-1:10,000
Functional Assays: 2-10ul
Optimal dilutions to be determined by the researcher.
Recommended Secondary AntibodiesI1904-39: IgG, X-Adsorbed (HRP) Pab Gt xRb
I1904-40A: IgG, H&L, X-Adsorbed (HRP) Pab Gt xRb
I1904-46Q: IgG, H&L (HRP) Pab Gt xRb
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid. No preservatives added.
PuritySerum
ImmunogenPurified human CYP2C9 expressed in E. coli.
SpecificityRecognizes human cytochrome p450 2C9 (CYP2C9).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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