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Anti -Cytochrome p450 2C9 (CYP2C9, (R)(S)-limonene 6-monooxygenase, (S)-limonene 6-monooxygenase, Cytochrome P450 PB-1, Cytochrome P450 MP-4, Cytochrome P450 MP-8, S-mephenytoin 4-hydroxylase)
Anti -Cytochrome p450 2C9 (CYP2C9, (R)(S)-limonene 6-monooxygenase, (S)-limonene
6-monooxygenase, Cytochrome P450 PB-1, Cytochrome P450 MP-4, Cytochrome P450 MP-8,
S-mephenytoin 4-hydroxylase)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
B N |
|
| P450 enzymes are divided into two groups: steroidogenic and xenobiotic. The latter group is comprised of three families 1, 2 and 3. The xenobiotic p450's are involved in most oxidative drug metabolism. Work in this area is ongoing but studies suggest that all known drug metabolism is mediated by family members: CYP3A, CYP2D6, CYP1A2, CYP2C9/10, CYP2C19 and CYP2E1. The product is a neutralizing antibody which is a potent inhibitor of CYP2C9 activity. Inhibition of CYP2C19 activity has also been observed. | | | Catalog # | C9095-15H | | Applications | Suitable for use in Western Blot and Functional assays. Other applications have not been tested. | | Recommended Dilutions | | | Western Blot: 1:5000-1:10,000 | | Functional Assays: 2-10ul | | Optimal dilutions to be determined by the researcher. | | Recommended Secondary Antibodies | I1904-39: IgG, X-Adsorbed (HRP) Pab Gt xRb | | I1904-40A: IgG, H&L, X-Adsorbed (HRP) Pab Gt xRb | | I1904-46Q: IgG, H&L (HRP) Pab Gt xRb | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid. No preservatives added. | | Purity | Serum | | Immunogen | Purified human CYP2C9 expressed in E. coli. | | Specificity | Recognizes human cytochrome p450 2C9 (CYP2C9). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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