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Anti -Cytochrome P450 3A4 (CYP3A4, HGNC:2637, CYP3A3, HLP, NF-25, P450C3, P450PCN1, Glucocorticoid inducible P450, Nifedipine Oxidase)
Anti -Cytochrome P450 3A4 (CYP3A4, HGNC:2637, CYP3A3, HLP, NF-25, P450C3, P450PCN1,
Glucocorticoid inducible P450, Nifedipine Oxidase)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
B N |
|
| Catalog # | C9095-15N | | P450 enzymes are divided into two groups | steroidogenic and xenobiotic. The latter group is comprised of three families 1, 2 and 3. The xenobiotic p450's are involved in most oxidative drug metabolism. Studies suggest that all known drug metabolism is mediated by family members:CYP3A, CYP2D6, CYP1A2, CYP2C9/10, CYP2C19 and CYP2E1. | | Applications | Suitable for use in Western Blot and Functional Assays. Other applications have not been tested. | | Recommended Dilution | Western Blot: 1:5000-1:10,000 | | Functional Assays: 2-20ul | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | Not Determined. | | Form | Supplied as a liquid. No preservatives or stabilizers added. | | Purity | Serum. | | Immunogen | Purified human CYP3A4 expressed in E.Coli. | | Specificity | Recognizes human cytochrome p450 3A4 (CYP3A4). The product is a neutralizing antibody which is a specific and potent inhibitor of CYP3A4. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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