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You are here:Home » Antibodies » Abs to Enzymes, Cytochrome » Anti -CYP3A4 (Cytochrome P450 3A4, Quinine 3-monooxygenase, CYPIIIA4, Nifedipine Oxidase, Cytochrome P450 3A3, CYPIIIA3, Cytochrome P450 HLp, Taurochenodeoxycholate 6-alpha-hydroxylase, Cytochrome P450 NF-25, Cytochrome P450-PCN1, Albendazole Monooxygenase, Alb

Anti -CYP3A4 (Cytochrome P450 3A4, Quinine 3-monooxygenase, CYPIIIA4, Nifedipine Oxidase,
Cytochrome P450 3A3, CYPIIIA3, Cytochrome P450 HLp, Taurochenodeoxycholate
6-alpha-hydroxylase, Cytochrome P450 NF-25, Cytochrome P450-PCN1, Albendazole
Monooxygenase, Alb

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Mouse Purified B IH
CYP3A4, is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs which are are used today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens.
Catalog #C9095-15N5
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot (Cell ysate): 1:500-1:1000 detects a band at ~57.34kD using HepG2 lysate
Western Blot (Tissue lysate): 1:500-1:1000 detecsts a band at ~57.34kD using human liver lysate
Western Blot (Transfected lysate): 1:1000-1:2000 detects a band at ~55.33kD using CYP3A4 transfected 293T lysate
Immunohistochemistry (paraffin): 3ug/ml using human small intestine tissue
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostMouse
SourceHuman
Concentration~1mg/Product Type: Pab
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified
ImmunogenFull-length human protein corresponding to aa1-503 from CYP3A4 (AAI01632.)
SpecificityRecognizes human CYP3A4.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.ml
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified
ImmunogenFull-length human protein corresponding to aa1-503 from CYP3A4 (AAI01632.)
SpecificityRecognizes human CYP3A4.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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