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You are here:Home » Antibodies » Abs to Enzymes, Cytochrome » Anti -Cytochrome P450 2B1,2B2

Anti -Cytochrome P450 2B1,2B2

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B
Phase 1 drug metabolism is catalyzed by two groups of monooxygenases, the cytochrome P450s (CYPs) and the flavin monooxygenases (FMOs). Both CYPs and FMOs are localized in the endoplasmic reticulum. Collectively, these enzymes catalyze the oxidation of a very broad range of substrates. Both classes are dependent on NADPH as a source of electrons, but the two classes exhibit significant differences in mechanism and substrate specificity.
Catalog #C9095-15T
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionsWestern Blot: 1:100 yields a strong band with 10ug of phenobarbital induced rat microsomes using alkaline phosphatase.
Optimum dilutions to be determined by researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG
Clone No4i184
HostMouse
SourceRat
ConcentrationNot Determined
FormSupplied in liquid.
PurityPurified
SpecificityRecognizes Cytochrome P450 (2B1 and 2B2).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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