You are here:Home
»
Antibodies
»
Abs to Enzymes, Cytochrome
»
Anti -Cytochrome P450 Enzyme CYP1A1 and CYP1A2
Anti -Cytochrome P450 Enzyme CYP1A1 and CYP1A2
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
E B |
|
| Cytochromes P450 enzymes are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. | | | Catalog # | C9095-18 | | Applications | Suitable for use in Western Blot and ELISA. Other applications not tested. | | Recommended Dilution | Western Blot: Useful for the simultaneous detection of CYP1A1 (57kD) and CYP1A2 (54kD), which can be separated electrophoretically. | | Optimal dilution determined by the researcher. | | Positive Control | Rat hepatic microsomal fraction. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Rat | | Concentration | Not determined | | Form | Supplied as a liquid. No preservative added. | | Purity | Serum | | Immunogen | Synthetic peptide | | Specificity | Recognizes rat Cytochrome P450 Enzyme CYP1A1 and CYP1A2 on Western Blots of hepatic microsomal fraction. Does not crossreact with other cytochrome P450 enzymes. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
