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You are here:Home » Molecular Biology » MB-Cloning-cDNA » Cytochrome P450 4A8, cDNA Probe, Human, BioGenomics™

Cytochrome P450 4A8, cDNA Probe, Human, BioGenomics™


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Phase 1 drug metabolism is catalyzed by two groups of monooxygenases, the cytochrome P450s (CYPs) and the flavin monooxygenases (FMOs). Both CYPs and FMOs are localized in the endoplasmic reticulum. Collectively, these enzymes catalyze the oxidation of a very broad range of substrates. Both classes are dependent on NADPH as a source of electrons, but the two classes exhibit significant differences in mechanism and substrate specificity.
Catalog #C9095-18Y
Size of the cDNA1.95Kb
Applications Suitable for use for synthesis, by standard random priming or nick translation techniques, of radiolabeled probes for investigations of P450 4A8 gene expression. Other applications not tested.
Optimum dilutions to be determined by researcher.
Storage and StabilityStable for at least one year at -70°C. Avoid repeated freeze/thaw cycles.
FormSupplied in TE buffer.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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