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You are here:Home » Antibodies » Antibodies-Enzymes, Cytochrome » Anti -CYP19A1, ID (Cytochrome P450 19A1, CYPXIX, Estrogen Synthetase, P-450AROM, Aromatase, Cytochrome P-450AROM, ARO1, CYAR, CYP19)

Anti -CYP19A1, ID (Cytochrome P450 19A1, CYPXIX, Estrogen Synthetase, P-450AROM,
Aromatase, Cytochrome P-450AROM, ARO1, CYAR, CYP19)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified B
CYP19A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation.
Catalog #C9095-19W3
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionsWestern Blot: 1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by ammonium sulfate precipitation
ImmunogenKLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids aa221-253 in the central region of CYP19A1, UniProt Accession #NP_000094; P11511
SpecificityRecognizes human CYP19A1 at ~58kD.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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