Anti -Cytochrome P450 19A1 (Cytochrome P450 Family 19 Subfamily A Polypeptide 1, CYP19A1, CYP19, CYPXIX, Aromatase, ARO, ARO1, ARO 1, CPV, CYAR, Estrogen Synthetase, MGC104309, P450AROM, P-450AROM)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B |
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| This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. [provided by RefSeq] | | | | | | Applications: | | | Suitable for use in ELISA and Western Blot. Other applications not tested. | | | Catalog # | C9095-19X | | Recommended Dilution | ELISA: 1:128,000 | | Western Blot: Western Blot 0.1-0.3ug/ml. | | Optimal dilutions to be determined by the researcher. | | Positive Control | Human placenta lysates. ~50-55kD | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in Tris-saline, pH 7.3, 0.5% BSA, 0.02% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide correspoding to C-HDLSLHPDETKN, from the internal region of the protein (NP_000094.2; NP_112503.1). | | | | Specificity | Recognizes human CYP19A1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Cytochrome P450 19A1 (Cytochrome P450 Family 19 Subfamily A Polypeptide 1, CYP19A1, CYP19, CYPXIX, Aromatase, ARO, ARO1, ARO 1, CPV, CYAR, Estrogen Synthetase, MGC104309, P450AROM, P-450AROM) |
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