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You are here:Home » Antibodies » Abs to Enzymes, Cytochrome » Anti -Cytochrome P450 26A1 (CYP26A1)

Anti -Cytochrome P450 26A1 (CYP26A1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IF
Cytochrome P450 (P450 or CYP) enzymes, a superfamily of b-type heme-containing proteins found in organisms from all
domains of life, are major catalysts in the oxidative
transformation of a diversity of endogenous and exogenous
compounds. CYP26A1 (Cytochrome P450, family 26, subfamily A, polypeptide 1) is a 497aa enzyme in mouse, rat and human (chr10q23). This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in the regulation of gene expression in both embryonic and adult tissues. Highest levels of expression are noticed in adult liver, heart, pituitary gland, adrenal gland, placenta and regions of the brain.
Catalog #C9095-29
ApplicationsSuitable for use in ELISA, Western Blot and Immunofluorescence. Other applications not tested.
Recommended DilutionELISA: 1:100,000 using 50-100ng control peptide per well
Western Blot: 1-10ug/ml using ECL technique
Optimal dilutions to be determined by the researcher.
Control PeptideC9095-29A-Cytochrome P450 26A1, Human, Control Peptide (CYP26A1)
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.2% BSA, 40% glycerol.
PurityPurified by immunoaffinity chromatography.
Immunogen15 amino acid synthetic peptide located at the N-terminus of human CYP26A1 (KLH). Species Sequence Homology: Mouse, rat - 100%; chicken - 73%.
SpecificityRecognizes human CYP26A1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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