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You are here:Home » Antibodies » Abs to Transport Proteins » Anti -Cytohesin 1 (B2-1, CLM1, CTH-1, CYTIP, Cytoadhesin 1, D17S811E, Homolog of Secretory Protein SEC7, Pleckstrin Homology Sec7 and Coiled/Coil Domains 1, PSCD1, PH, SEC7 and Coiled-coil Domain-containing Protein 1) (Azide Free)

Anti -Cytohesin 1 (B2-1, CLM1, CTH-1, CYTIP, Cytoadhesin 1, D17S811E, Homolog of Secretory
Protein SEC7, Pleckstrin Homology Sec7 and Coiled/Coil Domains 1, PSCD1, PH, SEC7 and
Coiled-coil Domain-containing Protein 1) (Azide Free)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH
The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. The encoded protein is 83% homologous to that of CYTH2. [provided by RefSeq]
Catalog #C9096-05E
ApplicationsSuitable for use in ELISA, Immunohistochemistry (paraffin), and Western Blot. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 1.5ug/ml
Western Blot: 1:500-1:1,000
ELISA: 1ug/ml-3ng/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No11C277
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant protein corresponding to a portion of amino acids within aa1-399 of human PSCD1.
SpecificityRecognizes human PSCD1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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