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Specifications

Clone Host Grade Applications Monoclonal Mouse Purified B IH IC FC

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in epithelial tissues by at least 20 different polypeptides. They range in molecular weight from between 40kD and 68kD and isoelectric pH between 4.9 – 7.8, The individual cytokeratin polypeptides are designated 1–20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies
Catalog #	C9097-14C
Applications	Western blot
	Immunohistochemistry on frozen tissue sections.
	Immunocytochemistry
	Flow cytometry
CAS Number	n/a
Clone Type	Monoclonal
Isotype	IgG3
Clone No	2Q1116
Host	Mouse
Source	Human
Concentration	~1mg/ml
Form	Supplied as a liquid in buffer with 0.1% sodium azide.
Purity	Purified IgG from culture supernatant.
Immunogen	Cytoskeletal preparation of TR146 epithelial cells.
Specificity	Reacts with basal cell compartments of stratified and combined epithelia. Recognizes human, porcine, rat and canine cytokeratin 14. Has not been tested on other species.
Important Note	This product is intended for research use only, not for use in human, therapeutic or diagnostic applications.