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You are here:Home » Antibodies » Antibodies-Cytokeratin » Anti -Cytokeratin 15 (Keratin 15, KRT15, CK15, CK-15, Cytokeratin-15, K15, K1CO, Keratin, type I cytoskeletal 15, KRTB)

Anti -Cytokeratin 15 (Keratin 15, KRT15, CK15, CK-15, Cytokeratin-15, K15, K1CO, Keratin,
type I cytoskeletal 15, KRTB)


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Clone Host Grade Applications
Monoclonal Mouse Purified IH
Keratins is a family of about 20 proteins that form intermediate filament in epithelial cells. Obligate heteropolymers of a type I and a type II subunit, they contribute to the structure and strength of the cytoskeleton. Mutations in keratin genes cause keratinopathies, inherited diseases of the skin and its appendages. Keratins include more than 20 unique gene products (termed K1-K20) that are divided into type I (K9-K20) and type II (K1-K8). Most epithelial cells express at least one type I and one type II keratin as their predominant intermediate filament protein complement in an epithelial cell-specific manner. Cytokeratin 15 belongs to the acidic or type I keratin family and assembles into a keratin filament network paired with K5, its basic, type II keratin expression partner. It is expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of fetal skin epidermis and nail Human K15 is encoded on chromosome 17q21.2.
Catalog #C9097-15B
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (formalin fixed paraffin embedded): 1:25-1:75
Optimal dilutions to be determined by the researcher.
Positive ControlSkin
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
Clone No11E148
ConcentrationNot determined
FormSupplied as a liquid, 0.05% sodium azide.
ImmunogenA 17-mer synthetic peptide corresponding to the C-terminus of human cytokeratin 15. Cellular Localization: Cytoplasmic.
SpecificityRecognizes human Cytokeratin 15. Species Crossreactivity: bovine, mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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