Anti -Cytokeratin 17 (Cytokeratin-17, CK 17, CK17, CK-17, K17, Keratin 17, Keratin-17,
Keratin Type I Cytoskeletal 17, KRT 17, KRT17, KRT17 Protein, PC, PC2, PCHC1)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Supernatant |
B IH IC FC IF |
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| Among the cytoplasmic intermediate filaments (IF) proteins, keratins make up the largest family and are expressed specifically in epithelial cells in a cell-specific manner. Keratins include more than 20 unique gene products (termed K1-K20) that are divided into type I (K9-K20) and type II (K1-K8). Most epithelial cells express at least one type I and one type II keratin as their predominant IF protein complement in an epithelial cell-specific manner. The protein encoded by this gene is a type I cytokeratin. It is expressed in abundance in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. It maps to 17q12-q21 region of human chromosome. It may be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial stem cells. | | | Catalog # | C9097-16D | | Applications | Suitable for use in Immunofluorescence, Flow Cytometry, Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. | | Recommended Dilution | Flow Cytometry: 1:25-1:200 | | Western Blot: 1:100-1:1000 | | Immunohistochemistry (formalin fixed paraffin embedded): 1:25-1:50 | | Immunohistochemistry: Frozen | | Optimal dilutions to be determined by the researcher. | | Positive Control | Skin | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2b | | Clone No | 11E150 | | Host | Mouse | | Source | Rat | | Concentration | Not determined. | | Form | Supplied as a liquid, 0.05% sodium azide. | | Purity | Supernatant | | Immunogen | Cytoskeletal fraction of rat colon epithelium. Cellular Localization: Cytoplasmic. | | Specificity | Recognizes rat Cytokeratin 17. Species Crossreactivity: human. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Cytokeratin 17 (Cytokeratin-17, CK 17, CK17, CK-17, K17, Keratin 17, Keratin-17, Keratin Type I Cytoskeletal 17, KRT 17, KRT17, KRT17 Protein, PC, PC2, PCHC1) |
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