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Specifications

Clone Host Grade Applications Monoclonal Mouse Purified B IH IC FC

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in epithelial tissues by at least 20 different polypeptides. They range in molecular weight from between 40kD and 68kD and isoelectric pH between 4.9 – 7.8, The individual cytokeratin polypeptides are designated 1–20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies
Catalog #	C9097-23H
Applications	Western blot
	Immunohistochemistry on frozen tissue sections.
	Immunocytochemistry
	Flow cytometry
Clone Type	Monoclonal
Isotype	IgG1
Clone No	2Q1118
Host	Mouse
Source	Human
Concentration	~1mg/ml
Form	Supplied as a liquid in buffer with 0.1% sodium azide.
Purity	Purified IgG from culture supernatant.
Immunogen	Cytoskeletal preparation of human bladder carcinoma cell line T24
Specificity	Reacts exclusively with human glandular epithelial cells of the digestive, respiratory and urogenital tracts, endocrine and exocrine cells and mesothelial cells as well as adenocarcinomas originating from them. Recognizes human only. Does not react with other species.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.