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You are here:Home » Antibodies » Abs to Cytokeratin » Anti -Cytokeratin 18

Anti -Cytokeratin 18

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified B IH IC FC
Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in epithelial tissues by at least 20 different polypeptides. They range in molecular weight from between 40kD and 68kD and isoelectric pH between 4.9 7.8, The individual cytokeratin polypeptides are designated 120. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies
Catalog #C9097-23H
ApplicationsWestern blot
Immunohistochemistry on frozen tissue sections.
Immunocytochemistry
Flow cytometry
Clone TypeMonoclonal
IsotypeIgG1
Clone No2Q1118
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in buffer with 0.1% sodium azide.
PurityPurified IgG from culture supernatant.
ImmunogenCytoskeletal preparation of human bladder carcinoma cell line T24
SpecificityReacts exclusively with human glandular epithelial cells of the digestive, respiratory and urogenital tracts, endocrine and exocrine cells and mesothelial cells as well as adenocarcinomas originating from them. Recognizes human only. Does not react with other species.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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