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You are here:Home » Antibodies » Abs to Cytokeratin » Anti -Cytokeratin 19 (Keratin, Type I Cytoskeletal 19, Cytokeratin-19, CK-19, Keratin-19, K19, KRT19)

Anti -Cytokeratin 19 (Keratin, Type I Cytoskeletal 19, Cytokeratin-19, CK-19, Keratin-19,
K19, KRT19)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant B IP IH IC IF
Among the cytoplasmic intermediate filaments (IF) proteins, keratins make up the largest family and are expressed specifically in epithelial cells in a cell-specific manner. Keratins include more than 20 unique gene products (termed K1-K20) that are divided into type I (K9-K20) and type II (K1-K8). Most epithelial cells express at least one type I and one type II keratin as their predominant IF protein complement in an epithelial cell-specific manner. Cytokeratin 19 (K19) is a type I intermediate filament protein that is expressed in stratified and simple-type epithelia. It is unique in that it has a very short 13aa tail domain. It possesses assembly properties and it may impart unique properties to the basal cells expressing it in skin epithelia. It maps to the 17q21.2 region oh human chromosome and has a molecular weight of 44,098D. It is expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles.
Catalog #C9097-24U
ApplicationsSuitable for use in Immunofluorescence, Western Blot, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 1:25-1:50
Optimal dilutions to be determined by the researcher.
Positive ControlSkin
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No11E154
HostMouse
SourceHuman
ConcentrationNot determined.
FormSupplied as a liquid, 0.05% sodium azide.
PuritySupernatant
ImmunogenDetergent insoluble extract of human mammary epithelium. Cellular Localization: Cytoplasmic.
SpecificityRecognizes human Cytokeratin 19.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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