Anti -Cytokeratin 4 (Cytokeratin-4, CK 4, CK4, CK-4, CYK4, FLJ31692, Keratin 4, Keratin-4,
Keratin Type II Cytoskeletal 4, K4, KRT4) (Azide Free)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Supernatant |
B IH IC FC IF |
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| Among the cytoplasmic intermediate filaments (IF) proteins, keratins make up the largest family and are expressed specifically in epithelial cells in a cell-specific manner. Keratins include more than 20 unique gene products (termed K1-K20) that are divided into type I (K9-K20) and type II (K1-K8). The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. The protein encoded by this gene is a type II cytokeratin and generally associated with keratin-13. It is expressed in abundance in expressed in the dorsal and ventral epithelium of the tongue with the highest expression levels being detected in the suprabasal layer. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. It maps to 12q12-q13 region of human chromosome. | | | Catalog # | C9097-35J | | Applications | Suitable for use in Immunofluorescence, Flow Cytometry, Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. | | Recommended Dilution | Flow Cytometry: 1:25-1:200 | | Western Blot: 1:100-1:1000 | | Immunohistochemistry (formalin fixed paraffin embedded): 1:25-1:50 | | Immunohistochemistry: Frozen | | Optimal dilutions to be determined by the researcher. | | Positive Control | Skin | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 11E157 | | Host | Mouse | | Source | Human | | Concentration | Not determined. | | Form | Supplied as a liquid, 0.05% sodium azide. | | Purity | Supernatant | | Immunogen | Cytokeratin purified from human esophagus. Cellular Localization: Cytoplasmic. | | Specificity | Recognizes human Cytokeratin 4. Species Crossreactivity: feline, canine. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Cytokeratin 4 (Cytokeratin-4, CK 4, CK4, CK-4, CYK4, FLJ31692, Keratin 4, Keratin-4, Keratin Type II Cytoskeletal 4, K4, KRT4) (Azide Free) |
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