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You are here:Home » Antibodies » Antibodies-Cytokeratin » Anti -Cytokeratin 5 + 14

Anti -Cytokeratin 5 + 14


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Clone Host Grade Applications
Monoclonal Mouse Purified IH IC IF
Basal cells of human epidermis express acidic cytokeratin 14 and basic cytokeratin 5. Cytokeratin 5 is a 58kD protein, which is closely related to cytokeratin 6. Cytokeratin 5 and 6 are expressed in basal cell epithelioma, basal cells of prostate, urothelium, vagina, squamous cell carcinomas of skin, tongue, epiglottis and rectal-anal region. Cytokeratin 5 can be useful in the distinction of mesotheliomas from most adenocarcinomas. Cytokeratin 14 belongs to the type A (acidic) subfamily of low MW cytokeratins and exists in combination with cytokeratin 15.
Catalog #C9097-37R
ApplicationsSuitable for use in Immunohistochemistry and Immunofluorescence/Immunocytochemistry. Other applications have not been tested.
Recommended DilutionsImmunofluorescence (IC): Neat
Immunohistochemistry: Neat
Optimal dilutions to be determined by the researcher.
Positive Control Skin
Storage and StabilityMay be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1, IgG3
Clone No8J1213
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH 7.2, 0.08% sodium azide.
ImmunogenProkaryotic recombinant protein corresponding to a 103 amino acid portion of C-terminal region of the human cytokeratin 5; Synthetic peptide corresponding to the extreme c-terminal of human keratin-14. Cellular Localization: Cytoplasmic
SpecificityRecognizes human cytokeratin 5 intermediate filament protein as well as to 50kD cytokeratin protein designated cytokeratin 14. This antibody can be useful to distinguish stratified epithelial cells from simple epithelial cells.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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