Anti -Cytokeratin 6 (Keratin 6, KRT6, K6irs, K6IRS2, KRT6IRS2, Cytokeratin-72, CK-72,
KB35, Keratin Type II Cytoskeletal 72, Keratin 72, Keratin-72, K72, KRT72, MGC142246,
Type-II Keratin Kb35, Type II Inner Root Sheath-specific Keratin-K6irs2)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Purified |
B IH |
|
| Among the cytoplasmic intermediate filaments (IF) proteins, keratins make up the largest family and are expressed specifically in epithelial cells in a cell-specific manner. Keratins include more than 20 unique gene products (termed K1-K20) that are divided into type I (K9-K20) and type II (K1-K8). The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. Keratin 6 is a type-II keratin. It exists in six different isomeric forms which associate with KRT16 and/or KRT17. Mutations in this gene have been associated with pachyonychia congenita. It maps to 12q12-q13 region of human chromosome. It is expressed in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. | | | Catalog # | C9097-38A | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (formalin fixed paraffin embedded): 1:25-1:75 | | Immunohistochemistry: Frozen | | Optimal dilutions to be determined by the researcher. | | Positive Control | Skin | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a | | Clone No | 11E162 | | Host | Mouse | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid, 0.05% sodium azide. | | Purity | Purified | | Immunogen | Synthetic peptide (GSSTIKYTTTS) corresponding to the C- terminus of human cytokeratin 6. Cellular Localization: Cytoplasmic. | | Specificity | Recognizes human Cytokeratin 6. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Cytokeratin 6 (Keratin 6, KRT6, K6irs, K6IRS2, KRT6IRS2, Cytokeratin-72, CK-72, KB35, Keratin Type II Cytoskeletal 72, Keratin 72, Keratin-72, K72, KRT72, MGC142246, Type-II Keratin Kb35, Type II Inner Root Sheath-specific Keratin-K6irs2) |
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