Anti -Cytokeratin 7, NT (Cytokeratin-7, CK 7, CK7, CK-7, Keratin 55k Type ii Cytoskeletal,
Keratin 7, Keratin-7, K7, KRT7, Keratin Simple Epithelial Type 1 K7, Keratin Type ii
Cytoskeletal 7, K2C7, MGC129731, MGC3625, Sarcolectin, SCL, Type ii Mesothelial Kerat
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP IH IC |
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| Keratins are cytoplasmic intermediate filament proteins expressed by epithelial cells. Keratin 7 (K7) is expressed in a wide range of epithelial structures in humans. The expression pattern in mice is similar to the reported human distribution, with substantial expression observed in lung, bladder, mesothelium, hair follicle, and ductal structures (1). Protein expression levels of CK7 appear significantly higher in chromophobe RCC compared to oncocytoma (p < 0.001). Studies provide further evidence that CK7 and parvalbumin immunostains may be useful in differentiating oncocytoma from chromophobe RCC in problematic cases (2). Also, the pattern of immunohistochemical expression of CK 7 along with CK 20 is commonly used to assess possible primary sites of metastatic carcinomas (3). | | | Catalog # | C9097-40L | | Applications | Suitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 1:2000 | | Immunoprecipitation: 1:30 | | Immunohistochemistry: 1:100-1:250 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in 50mM Tris-Glycine, pH 7.4, 0.18M sodium chloride, 0.25% sodium azide, 0.25mM EDTA, 25mM Citric Acid, 0.5% BSA, 40% glycerol. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to residues near the N-terminus of human CK-7. | | Specificity | Recognizes human Cytokeratin 7. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Cytokeratin 7, NT (Cytokeratin-7, CK 7, CK7, CK-7, Keratin 55k Type ii Cytoskeletal, Keratin 7, Keratin-7, K7, KRT7, Keratin Simple Epithelial Type 1 K7, Keratin Type ii Cytoskeletal 7, K2C7, MGC129731, MGC3625, Sarcolectin, SCL, Type ii Mesothelial Kerat |
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