Anti -Cytokeratin Type I and II (Keratin Type II Cytoskeletal 1, Keratin 1, Keratin-1, K1,
KRT1, KRT1A, Keratin Type II Cytoskeletal 2 Epidermal, Keratin 2, KRT2, KRT2A, Keratin-2
Epidermis, Keratin-2e, K2e, KRTE, KRT2E, 67kD Cytokeratin, Cytokeratin-1, CK1, CK
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Ascites |
B IH IC IF |
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| Cytokeratins are subfamily of intermediate filament protein, characterized by remarkable biochemical diversity. They are expressed specifically in epithelial cells represented by twenty different polypeptides. They range in molecular weight between 40kD and 68kD and isoelectric pH between 4.9 and 7.8. The cytokeratins are divided into type I and type II subgroups, the type II family members comprising the basic to neutral cytokeratin 1-8, while the type I comprises the acidic cyokeratins 9-20. Cytokeratin 11E165:11E402 is a mixture of two different clones of anti-cytokeratin monoclonal antibodies, 11E165 & 11E402. Both of these individual clones detect certain high and low molecular weight keratins. 11E165 detects the high molecular weight cytokeratins 10, 14, 15, and 16, and also the low molecular weight cytokeratin 19. Clone 11E402 detects the high molecular weight cytokeratins 1, 2, 3, 4, 5, and 6, and the low molecular weight cytokeratins 7 and 8. Thus cytokeratin 11E165+11E402 is a useful antibody cocktail having a broad reactivity. | | | Catalog # | C9097-57D | | Applications | Suitable for use in Immunofluorescence, Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (frozen): 1:10 -1:40 | | Immunohistochemistry (formalin fixed paraffin embedded): 1:25-1:50 | | Optimal dilutions to be determined by the researcher. | | Positive Control | Human tonsil | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 11E165+11E402 | | Host | Mouse | | Source | Human | | Concentration | Not determined. | | Form | Supplied as a liquid, 0.05% sodium azide. | | Purity | Ascites | | Immunogen | Human epidermal keratin. Cellular Localization: Cytoplasmic. | | Specificity | Recognizes human Cytokeratin 1 and 2. Species Crossreactivity: lizard, macaque, porcine, shrew. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Cytokeratin Type I and II (Keratin Type II Cytoskeletal 1, Keratin 1, Keratin-1, K1, KRT1, KRT1A, Keratin Type II Cytoskeletal 2 Epidermal, Keratin 2, KRT2, KRT2A, Keratin-2 Epidermis, Keratin-2e, K2e, KRTE, KRT2E, 67kD Cytokeratin, Cytokeratin-1, CK1, CK |
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