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You are here:Home » Antibodies » Abs to Infectious Disease CMV » Anti -Cytomegalovirus (blend)

Anti -Cytomegalovirus (blend)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites IH IF
Cytomegalovirus is an enveloped double stranded DNA virus which in humans (HCMV) is commonly known as human Herpes virus 5 (HHV-5). Glycoprotein B (gB) is the main antigenic protein within the envelope of HCMV. It is required for HCMV mediated membrane fusion along with the gH/gL complex. The unprocessed precursor of HCMV gB is 906 amino acids in length, with a MW of ~100kD.
Catalog #C9098
ApplicationsSuitable for use in Immunofluorescence and Immunohistochemistry. Other applications have not been tested.
Recommended DilutionsOptimal dilutions to be determined by researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No2Q1892
HostMouse
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH 7.6, 0.1% sodium azide.
PurityAscites
ImmunogenMRC-5 infected cells with ATCC VR538 and AD169, ultrasonicated, screened by plate reduction neutralization tests.
SpecificityRecognizes Cytomegalovirus. Reacts with Immediate early, early and late antigen preparations. Can detect CMV infection within 2 hours post-infection exhibiting a nuclear staining which reaches peak intensity between 48 and 96 hours. Can be detected during the complete CMV infection cycle. Staining of CMV structural antigens becomes apparent at about 48 hours. Extra-nuclear staining is first seen in the region of the golgi apparatus followed subsequently by staining of viral proteins and particles in the cytoplasm.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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