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You are here:Home » Antibodies » Abs to Neuroscience » Anti -DAF-3 (Abnormal Dauer Formation Protein 3, DAF 3)

Anti -DAF-3 (Abnormal Dauer Formation Protein 3, DAF 3)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum B IP
Signals from TGF-beta superfamily receptors are transduced to the nucleus by Smad proteins, which transcriptionally activate target genes. In Caenorhabditis elegans (C.elegans), defects in a TGF-beta-related pathway cause a reversible developmental arrest and metabolic shift at the dauer larval stage. DAF-3 transgenes interfere with dauer formation, playing a role in the nucleus. DAF-3 is unique in that it is antagonized, rather than activated, by a TGF-beta pathway.
Catalog #D1021-01A
ApplicationsSuitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
ConcentrationNot determined
FormAs reported
PuritySerum
ImmunogenA synthetic peptide made to the C-terminus (within residues 700-796) of the C.elegans DAF-3 protein.
SpecificitySpecies Crossreactivity: Can be used to detect C. elegans DAF-3 protein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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