USBio Logo

D1038-08 Mouse Anti-DAND5 (DAN domain family member 5, CER2, Cerberus-like protein 2, CERL2, Cerl-2, CKTSF1B3, COCO, CRL2, Cysteine knot superfamily 1, BMP antagonist 3, DAN domain family member 5, DANTE, DTE, FLJ38607, GREM3, Gremlin-3, MGC126849, SP1) (Biotin)

Specifications
Clone Type
Monoclonal
Host
Mouse
Source
Human
Conjugate
Biotin
Isotype
IgG1
Clone Number
9L819
Grade
Affinity Purified
Applications
E
Crossreactivity
Hu
Accession #
NP_689867
Shipping Temp
Blue Ice
Storage Temp
-20°C

DAND5, also known as COCO, Dante, and CKTSF1B3, is a member of the DAN Domain family of BMP antagonists that includes DAN, Gremlin, PRDC, and Cerberus. DAND5 binds and inhibits Xnr1, BMP-4, Activin, and Wnt8. It is implicated in gastrulation and embryonic left-right axis formation. Human DAND5 shares 60% and 24% aa sequence identity with mouse and Xenopus DAND5, respectively.

Applications
Suitable for use in ELISA. Other applications not tested.
Recommended Dilution
ELISA (Detection): 0.5-2ug/ml Optimal dilutions to be determined by the researcher.
Matched Pair
Capture: D1038-08A Detection: D1038-08
Storage and Stability
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Immunogen
Recombinant protein corresponding to Arg23-Ala189 from human DAND5, expressed in E. coli. Species Sequence Homology: mouse (60%), Xenopus (24%).
Form
Supplied as a lyophilized powder from PBS, 5% BSA. Labeled with Biotin. Reconstitute with 500ul sterile PBS.
Purity
Purified by Protein G affinity chromatography from hybridoma culture supernatant.
Specificity
Recognizes human DAND5. Does not crossreact or interfere with recombinant human ActivinA, recombinant human BMP-4, recombinant human DAN or recombinant mouse DAND5.
Conjugates
Pricing
Order
Proceed to Checkout
Cart Summary
ProductSizeListYour PriceQtyExt Price
Subtotal:Subtotal:
Subtotal:Subtotal:
Total Coupon Savings:Total Coupon Savings:()
Your cart is currently empty.
- Coupon Code
Recently Viewed
Contact Us

Visit our technical library or contact our support staff to answer your questions.

Telephone:
1-800-520-3011

Library | Contact

Distributors

For customers outside of the United States, please use one of our many distributors.

View Distributors

Payment Methods

We accept the following payment methods as well as pay-by-invoice.

MasterCard Visa PayPal
© 2023-2024 United States Biological - All Rights Reserved