You are here:Home
»
Molecular Biology
»
MB-Protein Kinase Inhibitors
»
Dasatinib, Free Base (N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide, BMS-354825)
Dasatinib, Free Base
(N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidin
yl]amino]-5-thiazolecarboxamide, BMS-354825)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Small molecule inhibitor of both the SRC and BCR/ABL tyrosine kinases, with IC50's for the isolated kinases of 0.55 and 3.0nM, respectively. | | | Catalog # | D1079-01 | | Melting Point | 274.5-276°C | | Solubility | Soluble in DMSO at 200mg/ml; very poorly soluble in ethanol; very poorly soluble in water; maximum solubility in plain water is estimated to be about 10uM; buffers, serum, or other additives may increase or decrease the aqueous solubility. | | Elemental Analysis | Calculated: | | C- 53.52% | | H - 6.08% | | Cl - 6.58% | | N: 18.20% | | S - 5.95% | | Storage and Stability | May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. | | CAS Number | 302962-49-8 | | Molecular Formula | C22H26ClN7O2S | | Molecular Weight | 488.01 | | Purity | ~99% | | Form | Supplied as a white to off-white powder | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
