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You are here:Home » Molecular Biology » MB-Protein Kinase Inhibitors » Dasatinib, Free Base (N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide, BMS-354825)

Dasatinib, Free Base
yl]amino]-5-thiazolecarboxamide, BMS-354825)


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Small molecule inhibitor of both the SRC and BCR/ABL tyrosine kinases, with IC50's for the isolated kinases of 0.55 and 3.0nM, respectively.
Catalog #D1079-01
Melting PointAs reported
SolubilitySoluble in DMSO at 200mg/ml; very poorly soluble in ethanol; very poorly soluble in water; maximum solubility in plain water is estimated to be about 10uM; buffers, serum, or other additives may increase or decrease the aqueous solubility.
Elemental AnalysisCalculated:
C- 53.52%
H - 6.08%
Cl - 6.58%
N: 18.20%
S - 5.95%
Storage and StabilityMay be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
CAS Number302962-49-8
Molecular FormulaC22H26ClN7O2S
Molecular Weight488.01
FormSupplied as a white to off-white powder
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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