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You are here:Home » Antibodies » Abs to Netrin » Anti -DCC (Netrin Receptor DCC, Colorectal Cancer Suppressor, Immunoglobulin Superfamily DCC Subclass Member 1, Tumor Suppressor Protein DCC, IGDCC1)

Anti -DCC (Netrin Receptor DCC, Colorectal Cancer Suppressor, Immunoglobulin Superfamily
DCC Subclass Member 1, Tumor Suppressor Protein DCC, IGDCC1)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified IH
Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.
Catalog #D1200-01B
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 2.5-5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-KQLNAITGSAF from aa1437-1447 of human DCC (NP_005206.2).
SpecificityRecognizes human DCC.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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