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You are here:Home » Antibodies » Abs to WD Repeat Proteins » Anti -DCAF6 (DDB1- and CUL4-associated Factor 6, Androgen Receptor Complex-associated Protein, ARCAP, IQ Motif and WD Repeat-containing Protein 1, Nuclear Receptor Interaction Protein, NRIP, IQWD1, MSTP055)

Anti -DCAF6 (DDB1- and CUL4-associated Factor 6, Androgen Receptor Complex-associated
Protein, ARCAP, IQ Motif and WD Repeat-containing Protein 1, Nuclear Receptor Interaction
Protein, NRIP, IQWD1, MSTP055)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
IQ motif and WD repeats 1 (IQWD1) WD-repeat proteins are a large family of eukaryotic proteins coordinating multi-protein complex assemblies and their role has been implicated in multiple cellular processes including signal transduction, transcriptional regulation, cell cycle control and apoptosis. NRIP is a novel 860aa nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up regulates their transcriptional activity, thereby functioning as a nuclear receptor coactivator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer thus indicating a therapeutic intervention. Northern Blot analysis detected a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.
Catalog #D1575-30A
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1-3ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenA portion of aa800-850 of human NRIP.
SpecificityRecognizes human NRIP. Species sequence homology: Canine, mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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