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Abs to DEAD Box Proteins
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Anti -DDX46 (DDX-46, DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 46)
Anti -DDX46 (DDX-46, DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 46)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP |
|
| This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing. | | | Catalog # | D1661-39 | | Applications | Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. | | Recommended Dilution | Immunoprecipitation: 2-5ug/mg lysate | | Western Blot: 1:2000-1:10,000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~0.2mg/ml | | Form | Supplied as a liquid in TBS, pH 7.2, 0.1% BSA, 0.1% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | The epitope recognized by this antibody maps to a region between residue 981 and the C-terminus (residue 1031) of human DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 using the numbering given in entry NP_055644.2 (GeneID 9879). | | Specificity | Species Crossreactivity: Human and Mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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