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You are here:Home » Antibodies » Abs to Lectins » Anti -Dectin 2 (Dendritic Cell-associated C-type Lectin 2, DC-associated C-type Lectin 2, Dectin-2, C-type Lectin Domain Family 6 Member A, CLEC6A, C-type Lectin Superfamily Member 10, CLECSF10)

Anti -Dectin 2 (Dendritic Cell-associated C-type Lectin 2, DC-associated C-type Lectin 2,
Dectin-2, C-type Lectin Domain Family 6 Member A, CLEC6A, C-type Lectin Superfamily Member
10, CLECSF10)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified IP IH FC
DC-associated C-type lectin-2 (Dectin-2), a type II transmembrane protein that is a member of the C-type lectin superfamily. In mouse, dectin-2 is predominantly expressed on tissue macrophages and some dendritic cells. Significant expression of Dectin-2 has been reported on macrophages in the red pulp and marginal zones of the spleen, kupffer cells in the liver and alveolar macrophages in the lung. Peripheral blood monocytes express low levels of dectin-2 but transient up-regulation of expression has been demonstrated on monocytes at sites of inflammation.
The function of Dectin-2 has not been fully determined but studies suggest a possible role in immune-surveillance.
Catalog #D1876-49D2
ApplicationsSuitable for use in Flow Cytometry, Immunohistochemistry and Immunoprecipitation. Other applications not tested.
Recommended DilutionFlow Cytometry: 1:50-1:100; 10ul labels 10e6 cells in 100ul
Immunohistochemistry: Frozen
Optimal dilutions to be determined by the researcher.
Recommended Secondary Antibodies Murine X-AdsorbedI1904-50U1 IgG H&L, X-Adsorbed Murine (HRP) Pab GtxRt
I1904-74H IgG, X-Adsorbed Murine (HRP) Pab GtxRt
1904-74F IgG, Murine X-Adsorbed (FITC) Pab GtxRt
I1903-13C IgG, H&L, X-Adsorbed Murine (PE) Pab GtxRt
I1903-13N IgG, H&L, X-adsorbed Murine (PE) Pab GtxRt
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No10B2695
HostRat
SourceMouse
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenDectin-2 (extracellular domain) Fc Fusion protein.
SpecificityRecognizes mouse Does not stain brain microglia or meningeal macrophages.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesClec4n


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