Anti -Deleted in Azoospermia-Like (DAZL, DAZL1, DAZ Homolog, DAZH, DAZ-like Autosomal,
DAZLA, MGC26406, SPGY-like-autosomal, SPGYLA)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Supernatant |
B IH |
|
| Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. | | | Catalog # | D2675-02 | | Applications | Suitable for use in Immunohistochemistry and Western Blot. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (parrafin): Does not require protein digestion pre-treatment of paraffin sections e.g. trypsin or pronase prior to staining. Requires antigen retrieval using heat treatment prior to staining of paraffin sections. | | Optimal dilutions to be determined by the researcher. | | Histology Positive Control Tissue | Ovary or testis. | | Hybridoma | Sp2/0 myeloma cells with spleen cells from T/O outbred mice. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 10B2706 | | Host | Mouse | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid, 0.09% sodium azide. | | Purity | Supernatant | | Immunogen | Synthetic peptide corresponding to sequence within the C terminal domain of human DAZL (CRVHHFRRSRAMLKSV). In adult germ cells, the expression of DAZL is localized to the cytoplasm. | | Specificity | Recognizes human DAZL, a member of the DAZ (deleted in azoospermia) family of RNA binding proteins. DAZL is expressed in fetal and adult testes and ovaries, and is believed to play a role in germ cell development. Species crossreactivity: mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | HGNC:2685, Deleted in Azoospermia-like 1, Deleted in Azoospermia-like Autosomal, Germline Specific RNA Binding Protein, Spermatogenesis Gene on the Y-like Autosomal |
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