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Abs to Notch Proteins
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Anti -Delta-like 1 (DLL1, Delta1, DL1, H-Delta-1, UNQ146/PRO172)
Anti -Delta-like 1 (DLL1, Delta1, DL1, H-Delta-1, UNQ146/PRO172)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B |
|
| Delta-1 acts as a ligand for Notch receptors. It blocks the differentiation of progenitor cells into the B-cell lineage while promoting cells with the characteristics of a T-cel/NK-cell precursor. It is expressed in heart and pancreas, with lower expression in brain and muscle and very little expression in placenta, lung, liver and kidney. Delta-1 is a transmembrane protein which is ubiquinated by MIB, leading to its endocytosis and subsequent degradation. It contains one DSL domain and eight EGF-like domains. | | | Catalog # | D2727-70A | | Applications | Suitable for use in ELISA and Western Blot. Other applications have not been tested. | | Recommended Dilutions | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20°C. Aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | 9G346 | | Host | Mouse | | Source | Human | | Concentration | As reported | | Form | Supplied as a lyophilized powder in PBS, pH7.4. Reconstitute with 100ul sterile ddH2O. | | Purity | Purified by affinity chromatography. | | Immunogen | Partial recombinant protein of human Delta-1 (aa18-109) with a GST tag. | | Specificity | Recognizes human Delta-like 1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Delta-like protein 1, Drosophila Delta homolog 1, H-Delta-1, GENE NAME: DLL1 |
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