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You are here:Home » Antibodies » Abs to Notch Proteins » Anti -Delta-like 1 (DLL1, Delta1, DL1, H-Delta-1, UNQ146/PRO172)

Anti -Delta-like 1 (DLL1, Delta1, DL1, H-Delta-1, UNQ146/PRO172)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
Delta-1 acts as a ligand for Notch receptors. It blocks the differentiation of progenitor cells into the B-cell lineage while promoting cells with the characteristics of a T-cel/NK-cell precursor. It is expressed in heart and pancreas, with lower expression in brain and muscle and very little expression in placenta, lung, liver and kidney. Delta-1 is a transmembrane protein which is ubiquinated by MIB, leading to its endocytosis and subsequent degradation. It contains one DSL domain and eight EGF-like domains.
Catalog #D2727-70A
ApplicationsSuitable for use in ELISA and Western Blot. Other applications have not been tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20°C. Aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG
Clone No9G346
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a lyophilized powder in PBS, pH7.4. Reconstitute with 100ul sterile ddH2O.
PurityPurified by affinity chromatography.
ImmunogenPartial recombinant protein of human Delta-1 (aa18-109) with a GST tag.
SpecificityRecognizes human Delta-like 1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesDelta-like protein 1, Drosophila Delta homolog 1, H-Delta-1, GENE NAME: DLL1


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