Anti -Der1-like Domain Family, Member 1 (DER-1, DER1, DERL1, DERLIN-1, DERTRIN-1,
FLJ13784, FLJ42092, MGC3067, PRO2577)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
|
| Derlin-1 is a channel-like protein, found in the ER membrane, responsible for degrading and funneling misfolded proteins and other cellular debris into the appropriate degradative pathways within the cell. | | | Catalog # | D3206-97B | | Cellular Localization | Subcellular localization in the endoplasmic reticulum | | Positive Control | KRM (canine microsome) lysates. (BD offers commercial liver microsomes) | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | As reported | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | A synthetic peptide made to the C-terminal region of the human Derlin-1 protein sequence (between residues 200-251). | | Specificity | This antibody is specific for Derlin-1. Species Crossreactivity: This antibody reacts with human and canine Derlin-1. No other specie has been tested. The immunogen used for this antibody production has 100% homology with human, Xenopus, bovine, and mouse protein. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Degradation in endoplasmic reticulum protein 1, Der1-like protein 1, DERtrin-1, DERL1 |
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