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You are here:Home » Antibodies » Abs to Membrane Proteins » Anti -Der1-like Domain Family, Member 1 (DER-1, DER1, DERL1, DERLIN-1, DERTRIN-1, FLJ13784, FLJ42092, MGC3067, PRO2577)

Anti -Der1-like Domain Family, Member 1 (DER-1, DER1, DERL1, DERLIN-1, DERTRIN-1,
FLJ13784, FLJ42092, MGC3067, PRO2577)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Derlin-1 is a channel-like protein, found in the ER membrane, responsible for degrading and funneling misfolded proteins and other cellular debris into the appropriate degradative pathways within the cell.
Catalog #D3206-97B
Cellular Localization Subcellular localization in the endoplasmic reticulum
Positive Control KRM (canine microsome) lysates. (BD offers commercial liver microsomes)
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormAs reported
PurityPurified by immunoaffinity chromatography.
ImmunogenA synthetic peptide made to the C-terminal region of the human Derlin-1 protein sequence (between residues 200-251).
SpecificityThis antibody is specific for Derlin-1. Species Crossreactivity: This antibody reacts with human and canine Derlin-1. No other specie has been tested. The immunogen used for this antibody production has 100% homology with human, Xenopus, bovine, and mouse protein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesDegradation in endoplasmic reticulum protein 1, Der1-like protein 1, DERtrin-1, DERL1


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