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You are here:Home » Antibodies » Abs to Drugs » Anti -Desipramine (Norpramin®, Pertofrane®)

Anti -Desipramine (Norpramin®, Pertofrane®)

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Specifications

Clone Host Grade Applications
Polyclonal Sheep Purified E
Desipramine is an active metabolite of imipramine and has been found to be useful in the treatment of neuropathic pain. It may also be used to treat symptoms of cocaine withdrawal. Desipramine is a tricyclic antidepressant (TCA). Tricyclic antidepressants contain a characteristic three ringed nucleus structure. They act primarily as serotonin­norepinephrine reuptake inhibitors. Tricyclic antidepressants are mainly used as antidepressants, but have also been for the treatment of anxiety disorders and attention hyperactivity disorder and as an adjunct to certain analgesics to treat chronic pain. In many treatments they have been replaced by other compounds with fewer side­effects.
Catalog #D3219-92A
Tricyclic antidepressants are not considered addictive and have a low abuse potential, but suddenly discontinuing treatment may results in discontinuation syndrome and overdose is a main cause of death from prescription drugs. They have significant cardiovascular and neurological toxicity. Monitoring of TCA levels can help determine toxicity, monitor compliance and establish individual target concentrations.
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended Dilution:
ELISA: 5.0ug/ml
Optimal dilutions to be determined by the researcher.
Match To D3219-92B
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostSheep
Concentration~1mg/ml (U.V. abs)
FormSupplied as a liquid in 20mM PBS, 0.09% sodium azide, pH 7.2.
PurityPurified.
ImmunogenDesipramine-BTG.
SpecificityRecognizes Desipramine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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