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You are here:Home » Antibodies » Abs to Extracellular Matrix Proteins » Anti -Desmin (DES, CMD1I, CSM1, CSM2, FLJ12025, FLJ39719, FLJ41013, FLJ41793, Intermediate Filament Protein)

Anti -Desmin (DES, CMD1I, CSM1, CSM2, FLJ12025, FLJ39719, FLJ41013, FLJ41793, Intermediate
Filament Protein)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant IH
Desmin, a protein of 53kD, is an intermediate filament protein of both smooth and striated muscles. Antibody to desmin reacts with striated (skeletal and cardiac) as well as smooth muscle cells. In skeletal and cardiac muscles, the staining is confined to the Z-bands giving a characteristic striated appearance. Anti-desmin antibody is useful in identification of tumors of myogenic origin. It reacts with leiomysarcomas (smooth muscle) as well as rhabdomysarcomas (striated muscle).
Catalog #D3221-03A
ApplicationsSuitable for use in Immunohistochemistry (Frozen). Other applications not tested.
Recommended DilutionOptimal dilution determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No6A402
HostMouse
SourceHuman
FormSupplied as a liquid in PBS, pH 7.4, 1% BSA and 0.09% sodium azide.
PurityTissue Culture Supernatant
ImmunogenPurified Human desmin.
SpecificityReacts with human desmin in skeletal, cardiac and smooth muscle cells. The antibody recognizes tumors of myogenic origin such as leiomyosarcomas and rhabdomyosarcomas. Species Cross Reactivity: Reported to crossreact with ovine (1), feline (2), rat, chicken, hamster, mouse (3) and human desmin.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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