Anti -Desmin (DES, CMD1I, CSM1, CSM2, FLJ12025, FLJ39719, FLJ41013, FLJ41793, Intermediate
Filament Protein)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Supernatant |
IH IF |
|
| Desmin is an intermediate filament protein of both smooth and striated muscles. Antibody to desmin reacts with striated (skeletal and cardiac) as well as smooth muscle cells. In skeletal and cardiac muscles, the staining is confined to the Z-bands giving a characteristic striated appearance. Anti-desmin antibody is useful in identification of tumors of myogenic origin. It reacts with leiomysarcomas (smooth muscle) as well as rhabdomysarcomas (striated muscle). | | | Catalog # | D3221-10 | | Applications | Suitable for use in Immuofluorescence and Immunohistochemistry. Other applications have not been tested. | | Recommended Dilution | Immunohistochemistry (Formalin/paraffin): 1:50-1:100 for 20 min at RT. No special pretreatment is required prior to staining. | | Optimal dilutions to be determined by the researcher. | | Positive Control | Muscle or sarcoma | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1,k | | Clone No | 0.N.247 | | Host | Mouse | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid, 0.09% sodium azide. | | Purity | Tissue culture supernatant | | Immunogen | Desmin from human muscle. Cellular Localization | | Specificity | Recognizes human Desmin. Species Crossreactivity: Baboon, monkey, bovine, feline, canine, hamster, rat and chicken. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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