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You are here:Home » Antibodies » Abs to Extracellular Matrix Proteins » Anti -Desmin (DES, CMD1I, CSM1, CSM2, FLJ12025, FLJ39719, FLJ41013, FLJ41793, Intermediate Filament Protein)

Anti -Desmin (DES, CMD1I, CSM1, CSM2, FLJ12025, FLJ39719, FLJ41013, FLJ41793, Intermediate
Filament Protein)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant IH
Desmin is a 53kD intermediate filamentprotein expressed in the cytoplasmic of both smooth and striated muscles. D3221-10J reacts with both striated (skeletal and cardiac) and smooth muscle cells. In skeletal and cardiac muscles, this antibody stains Z-bands giving a characteristic striated appearance. D3221-10J is also useful in identifying tumors of myogenic origin, including rhabdomyosarcomas (striated muscle) and leiomyosarcomas (smooth muscle).
Catalog #D3221-10J
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (formalin fixed paraffin embedded): 1:25-1:50
Immunohistochemistry (frozen): 1:25-1:100
Optimal dilutions to be determined by the researcher.
Positive ControlLeiomyoma
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No11E168
HostMouse
SourceHuman
ConcentrationNot determined.
FormSupplied as a liquid, 0.05% sodium azide.
PuritySupernatant
ImmunogenPurified desmin from human muscle.
SpecificityRecognizes human Desmin. Species Crossreactivity: baboon, feline, chicken, bovine, canine, hamster, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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