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You are here:Home » Antibodies » Abs to Extracellular Matrix Proteins » Anti -Desmoglein 1 (Desmosomal Glycoprotein 1, DG1, DGI, DSG1, DSG, CDHF4, Pemphigus Foliaceus Antigen, PPKS1, SPPK1)

Anti -Desmoglein 1 (Desmosomal Glycoprotein 1, DG1, DGI, DSG1, DSG, CDHF4, Pemphigus
Foliaceus Antigen, PPKS1, SPPK1)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus.
Catalog #D3221-82E
ApplicationsSuitable for use in ELISA. Other applications have not been tested.
Recommended Dilutions
Peptide ELISA Titer: 1:32,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
PurityPurified by peptide affinity chromatography.
ImmunogenSynthetic peptide corresponding to C-YTTSDTLKPSVHVHD, from the internal region of human Desmoglein 1 (NP_001933.2).
SpecificityRecognizes Desmoglein 1. Species sequence homology: human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namespemphigus foliaceus antigen, desmosomal glycoprotein 1, DSG, DG1, CDHF4, desmoglein 1, DSG1


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