Anti -Desmoglein 2 (Desmoglein-2, DSG2, ARVC10, ARVD10, Cadherin Family Member 5, CDHF5,
CMD1BB, HDGC, MGC117034, MGC117036, MGC117037)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B IP IF |
|
| Desmoglein 2 is a member of the desmosomal cadherin family that comprise the desmogleins and desmocollins. Desmosomes are cell-cell junctions in most epithelial cells and serve to link the intermediate filament cytoskeletons of adjacent cells. Within the desmosome the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 2 is synthesized in the basal layers, depending on the certain types of epidermis. | | | Catalog # | D3221-83F | | Applications | Suitable for use in Immunofluorescence, Western Blot and Immunoprecipitation. Other applications not tested. | | Recommended Dilution | Immunofluorescence: 1:10 | | Western Blot: 1:10 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 6D8 | | Host | Mouse | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Specificity | Recognizes human desmoglein 2 at ~165kD. Does not crossreact with desmoglein 1 or desmoglein 3. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
|
|
Questions or comments about this product? Inquire here. |
|
|
Download Specifications for Anti -Desmoglein 2 (Desmoglein-2, DSG2, ARVC10, ARVD10, Cadherin Family Member 5, CDHF5, CMD1BB, HDGC, MGC117034, MGC117036, MGC117037) |
External Links
|
