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You are here:Home » Antibodies » Abs to Disease Markers » Anti -Diaphanous 1 (hDia1, DIAPH1, p140DIA, DFNA1, LFHL1, diaphanous homolog 1, DRF1, Diaphanous-related formin 1, LFHL1, low frequency hearing loss 1, deafness, autosomal dominant 1)

Anti -Diaphanous 1 (hDia1, DIAPH1, p140DIA, DFNA1, LFHL1, diaphanous homolog 1, DRF1,
Diaphanous-related formin 1, LFHL1, low frequency hearing loss 1, deafness, autosomal
dominant 1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Diaphanous 1 is a member of the Formin homology (FH) family of cytoskeletal organizer proteins. It is required for cytokinesis and transcriptional activation of the serum response factor. It has also been suggested to contribute to localized actin polymerization and stress fiber formation, both by recruiting profiling to sites of Rho action and by cooperating with ROCK. The human Diaphanous 1 gene is associated with Premature Ovarian Failure (POF) and Nonsyndromic Deafness (DFNA1), an autosomal dominant, fully penetrant progressive hearing loss.
Catalog #D3470-01A
Positive Control 293T cell extracts
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormAs reported
PurityPurified by immunoaffinity chromatography.
ImmunogenA synthetic peptide, which represented a portion of human diaphanous homolog 1 encoded within exon 27 (LocusLink ID 1729).
SpecificitySpecies Crossreactivity: Human. Other species have not been tested. Reactivity with mouse Dia1 is likely owing to complete identity between peptide used for this antibody production and mouse ortholog.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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