Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Disease Markers » Anti -Diaphanous 1 (hDia1, DIAPH1, p140DIA, DFNA1, LFHL1, diaphanous homolog 1, DRF1, Diaphanous-related formin 1, LFHL1, low frequency hearing loss 1, deafness, autosomal dominant 1)

Anti -Diaphanous 1 (hDia1, DIAPH1, p140DIA, DFNA1, LFHL1, diaphanous homolog 1, DRF1,
Diaphanous-related formin 1, LFHL1, low frequency hearing loss 1, deafness, autosomal
dominant 1)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Catalog #D3470-01B
ApplicationsSuitable for use in ELISA and Western Blot. Other applications have not been tested.
Recommended Dilutions
Peptide ELISA Titer: 1:32,000
Western Blot: 0.3-1ug/ml ~140kD band observed in lysates of cell line NIH3T3 (calculated MW of 141kD according to Human NP_005210.3 and 139kD according to Mouse NP_031884.1).
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
PurityPurified by peptide affinity chromatography.
ImmunogenSynthetic peptide corresponding to C-QTKTSKAKKDQ, from the internal region of human Diaphanous 1 (NP_005210.3; NP_001073280.1).
SpecificityRecognizes Diaphanous 1. Species crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesdiaphanous-related formin 1, diaphanous-1, diaphanous 1, hDIA1, LFHL1, FLJ25265, DRF1, DIA1, DFNA1, diaphanous homolog 1 (Drosophila), DIAPH1, DFNA1, DIA1, DIAP1, Diaphanous-related formin-1, DRF1, FLJ25265, hDIA1, LFHL1, Protein diaphanous homolog 1


External Links