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You are here:Home » Antibodies » Abs to Neuroscience » Anti -Diazepam Binding Inhibitor (DBI, Acyl-CoA-binding Protein, ACBP, Endozepine, EP)

Anti -Diazepam Binding Inhibitor (DBI, Acyl-CoA-binding Protein, ACBP, Endozepine, EP)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites E B IP IH
Diazepam Binding Inhibitor (DBI) is a highly conserved 10kD polypeptide which is expressed in various species range from yeast to mammals. As an inverse agonist for benzodiazepine receptors, DBI downregulates inhibitory effects of GABA. It also has potential to induce anxiety. Found in central andperipheral tissues, DBI also participates in metabolism of steroids, which has been known to partially modify GABAA receptor function in the CNS. In peripheral tissues, DBI plays regulatory roles in steroidogenesis. DBI levels have been reported to be decreased in the cerebrospinal fluid obtained from patients with Alzheimer disease.
Catalog #D3475-02A
ApplicationsSuitable for use in ELISA, Western Blot, Immunohistochemistry, and Immunoprecipitation. Other applications not tested.
Recommended DilutionWestern Blotting: 1:100-500
Immunoprecipitation: 1-2ug/ml lysates
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b, k
Clone No10K186
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, 50% glycerol.
PurityAscites
ImmunogenRecombinant human GST fusion protein purified from E.coli.
SpecificityRecognizes human Diazepam Binding Inhibitor.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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