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You are here:Home » Antibodies » Abs to Disease Markers » Anti -Deafness Dystonia Protein 1, CT (Mitochondrial Import Inner Membrane Translocase Subunit Tim8 A, TIMM8A, X-linked Deafness Dystonia Protein, DDP1, DDP, TIM8A)

Anti -Deafness Dystonia Protein 1, CT (Mitochondrial Import Inner Membrane Translocase
Subunit Tim8 A, TIMM8A, X-linked Deafness Dystonia Protein, DDP1, DDP, TIM8A)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. It is also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane and acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70kD complex mediates the import of much more proteins. It is probably necessary for normal neurologic development.
Catalog #D3490-01
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Numbern/a
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.25mg/ml
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by ammonium sulfate precipitation.
ImmunogenSynthetic peptide selected from the C-terminal region of human TIMM8A (KLH).
SpecificityRecognizes human TIMM8A. Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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