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You are here:Home » Biochemicals » Biochem-Antibiotics » Ivermectin B1b (Dihydroavermectin B1b, 22, 23-Dihydroavermectin B1b )

Ivermectin B1b (Dihydroavermectin B1b, 22, 23-Dihydroavermectin B1b )


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Ivermectin B1b is the minor component (>20%) of the commercial anthelmintic, ivermectin. Members of the avermectin/milbemycin anthelmintic class exert their anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. The avermectin/milbemycins are also potent insecticides. In vitro tests have found the B1b (25-iso-propyl) analogue to be slightly more potent than the 25-sec-butyl (B1a) analogue as an inhibitor of nematode larval development and paralysis and also a more sensitive probe for ivermectin resistance.
Catalog #D3570-04A
Soluble in ethanol, methanol, DMF or DMSO.
CAS Number70209-81-3
Molecular FormulaC47H72O14
Molecular Weight861.1
SourceStreptomyces sp.
Purity>95% by HPLC
FormWhite solid
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesIvermectin B1b, 22, 23-Dihydroavermectin B1b

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