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You are here:Home » Biochemicals » Biochem-Inhibitors » Dimethyloxaloylglycine (DMOG)

Dimethyloxaloylglycine (DMOG)

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Specifications

DMOG is a cell permeable prolyl-4-hydroxylase inhibitor which upregulates HIF activity. HIF activation stimulates angiogenesis in several different models (1nM). DMOG also inhibits FIH (factor inhibiting HIF), an asparaginyl hydroxylase, which enhances the HIF response. It is active in vivo and attenuates myocardial injury in a rabbit ischemia reperfusion model (20mg/Kg).
Catalog #D3693-41
Melting Point 46-48°C
Solubility DMSO, ethanol, methanol
Storage and StabilityMay be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
CAS Number89464-63-1
Molecular FormulaC6H9NO5
Molecular Weight175.14
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
Alternate namesDMOG


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