Anti -DKK2 (DKK2, SK, DKK-2, dickkopf homolog 2 (Xenopus laevis), dickkopf-2 like,
dickkopf (Xenopus laevis) homolog 2)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B |
|
| This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). | | | Catalog # | D3795-03C | | Applications | Suitable for use in ELISA and Western Blot. Other applications have not been tested. | | Recommended Dilutions | | | Peptide ELISA Titer: 1:8000 | | Western Blot: 1-3ug/ml ~ 28kD band observed in Human Heart lysate (calculated MW of 28.5kD according to NP_055236). | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide. | | Purity | Purified by peptide affinity chromatography. | | Immunogen | Synthetic peptide corresponding to ATYSSKARLHVCQKI, from the C Terminus of human DKK2 (NP_055236.1). | | Specificity | Recognizes human DKK2. Species sequence homology: mouse, rat, canine, bovine. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Dickkopf related protein-2, dickkopf homolog 2, dickkopf 2, dickkopf (Xenopus laevis) homolog 2, Dickkopf gene 2, DKK-2, dickkopf homolog 2 (Xenopus laevis), DKK2 |
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