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You are here:Home » Antibodies » Abs to Dickkopf Proteins » Anti -DKK2 (DKK2, SK, DKK-2, dickkopf homolog 2 (Xenopus laevis), dickkopf-2 like, dickkopf (Xenopus laevis) homolog 2)

Anti -DKK2 (DKK2, SK, DKK-2, dickkopf homolog 2 (Xenopus laevis), dickkopf-2 like,
dickkopf (Xenopus laevis) homolog 2)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6).
Catalog #D3795-03C
ApplicationsSuitable for use in ELISA and Western Blot. Other applications have not been tested.
Recommended Dilutions
Peptide ELISA Titer: 1:8000
Western Blot: 1-3ug/ml ~ 28kD band observed in Human Heart lysate (calculated MW of 28.5kD according to NP_055236).
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
PurityPurified by peptide affinity chromatography.
ImmunogenSynthetic peptide corresponding to ATYSSKARLHVCQKI, from the C Terminus of human DKK2 (NP_055236.1).
SpecificityRecognizes human DKK2. Species sequence homology: mouse, rat, canine, bovine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesDickkopf related protein-2, dickkopf homolog 2, dickkopf 2, dickkopf (Xenopus laevis) homolog 2, Dickkopf gene 2, DKK-2, dickkopf homolog 2 (Xenopus laevis), DKK2


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