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Specifications

Clone Host Grade Applications Monoclonal Mouse Purified IH IC FC

dsDNA (double stranded deoxyribonucleic acid) is the genetic material of all cells and many viruses and is a polymer of nucleotides. The monomer consists of phosphorylated 2-deoxyribose N-glycosidically linked to one of four bases, adenine, cytosine, guanine or thymine. These are linked together by 3',5'-phosphodiester bridges. In the Watson-Crick double-helix model, two complementary strands are wound in a right-handed helix and held together by hydrogen bonds between complementary base pairs.
Catalog #	D3878-13B
Applications	Suitable for use in Flow Cytometry, Immunohistochemistry and Immunocytochemistry. Other applications not tested.
Recommended Dilution	Immunohistochemistry: Paraformaldehyde fixed or frozen tissue and formalin fixed paraffin-embedded tissue sections.
	Optimal dilutions to be determined by the researcher.
Positive Control	Tonsil tissue
Storage and Stability	May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Number	n/a
Clone Type	Monoclonal
Isotype	IgG3
Clone No	AE-2
Host	Mouse
Source	Human
Concentration	~0.1mg/ml
Form	Supplied as a liquid in PBS, 0.05% sodium azide.
Purity	Purified
Immunogen	Nuclei of Raji Burkitt’s lymphoma cells
Specificity	Recognizes double stranded DNA expressed in the nucleus of human cells. Produces a homogeneous staining pattern in the nucleus of normal and malignant cells.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names	Double-stranded DNA