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Anti -DNA Methyltransferase 1 (DNMT, MCMT, M.Hsa1, DNA (cytosine-5-)-methyltransferase 1, DNA MTase Mmu1, M.HsaI)
Anti -DNA Methyltransferase 1 (DNMT, MCMT, M.Hsa1, DNA (cytosine-5-)-methyltransferase
1, DNA MTase Mmu1, M.HsaI)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP |
|
| DNMT1 is a nuclear enzyme with a major role in the maintenance of DNA methylation patterns after replication. DNA methylation is significant for epigenetic regulation of gene expression, X chromosome inactivation, genomic imprinting, and development. Overexpression of DNMT1 has been detected in several human cancers. | | | Catalog # | D3931-61G | | Blocking Peptide | D3931-61T | | Applications | Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. | | Recommended Dilution | Western Blot: 1:5001: 5,000 | | Immunoprecipitation: 2-4 ug/mg protein | | Optimal dilution determined by the researcher. | | Recommended Secondary Reagents | Sheep anti rabbit IgG: HRP | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris-citrate/phosphate buffer, pH 7.5, 0.02% sodium azide, before the addition of glycerol to 40%. | | Purity | Purified by affinity chromatography. | | Immunogen | Synthetic peptide corresponding to a region within human DNMT1 encoded within exon 25. | | Specificity | Recognizes human DNA (cytosine-5) methyltransferase 1, also known as DNMT1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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