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You are here:Home » Antibodies » Abs to Enzymes, Methyltransferase » Anti -DNA Methyltransferase 2 (Dnmt2, DNA Cytosine 5 Methyltransferase 2 Like Protein 2, DNA Methyltransferase Homolog HsaIIP, PuMet)

Anti -DNA Methyltransferase 2 (Dnmt2, DNA Cytosine 5 Methyltransferase 2 Like Protein 2,
DNA Methyltransferase Homolog HsaIIP, PuMet)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B
Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting and is essential for mammalian development. Dnmt2 is expressed at low levels in adult tissues and its inactivation does not affect DNA methylation or maintenance of methylation. Dnmt2 contains all the sequence motifs diagnostic of DNA (cytosine-5)-methyltransferases but appears to lack the large N-terminal regulatory domain common to other eukaryotic methyltransferases.
Catalog #D3931-62A
Cellular Localization Nuclear
Positive Control transfected cell lysate
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG
Clone No8J1284
HostMouse
SourceMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenThis antibody was raised against synthetic peptides corresponding to mouse Dnmt2.
SpecificityIn mouse Dnmt2 transfected cell lysate, a 42kD band is oberseved. Species Crossreactivity: Crossreacts with Mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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