You are here:Home
»
Antibodies
»
Abs to Enzymes, Methyltransferase
»
Anti -DNA Methyltransferase 2 (Dnmt2, DNA Cytosine 5 Methyltransferase 2 Like Protein 2, DNA Methyltransferase Homolog HsaIIP, PuMet)
Anti -DNA Methyltransferase 2 (Dnmt2, DNA Cytosine 5 Methyltransferase 2 Like Protein 2,
DNA Methyltransferase Homolog HsaIIP, PuMet)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B |
|
| Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting and is essential for mammalian development. Dnmt2 is expressed at low levels in adult tissues and its inactivation does not affect DNA methylation or maintenance of methylation. Dnmt2 contains all the sequence motifs diagnostic of DNA (cytosine-5)-methyltransferases but appears to lack the large N-terminal regulatory domain common to other eukaryotic methyltransferases. | | | Catalog # | D3931-62A | | Cellular Localization | Nuclear | | Positive Control | transfected cell lysate | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | 8J1284 | | Host | Mouse | | Source | Mouse | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | This antibody was raised against synthetic peptides corresponding to mouse Dnmt2. | | Specificity | In mouse Dnmt2 transfected cell lysate, a 42kD band is oberseved. Species Crossreactivity: Crossreacts with Mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
