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You are here:Home » Antibodies » Abs to Enzymes, Methyltransferase » Anti -Dnmt2, NT (Putative DNA Cytosine Methyltransferase DNMT2, DNA Methyltransferase Homolog MmuIIP, DNA MTase Homolog MmuIIP, M.MmuIIP, Met-2, tRNA (Cytosine-5-)-methyltransferase, DNA (Cytosine-5)-methyltransferase-like Protein 2, DNA Methyltransferase Homol

Anti -Dnmt2, NT (Putative DNA Cytosine Methyltransferase DNMT2, DNA Methyltransferase
Homolog MmuIIP, DNA MTase Homolog MmuIIP, M.MmuIIP, Met-2, tRNA
(Cytosine-5-)-methyltransferase, DNA (Cytosine-5)-methyltransferase-like Protein 2, DNA
Methyltransferase Homol

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
mDnmt2 does not appear to be active as a DNA methyltransferase; however, its strong binding to DNA suggests that it may mark specific sequences in the genome by binding to DNA through the specific target-recognizing motif. mDnmt2 is strongly expressed in thymus, testis, and at much lower levels in spleen, lung, brain, heart, kidney, liver, skeletal muscle and embryonic stem cells. This protein belongs to the 5-cystosine methyltransferase family.
Catalog #D3931-62D
ApplicationsSuitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide selected from the N-terminal region of mouse Dnmt2 (KLH).
SpecificityRecognizes human Dnmt2. Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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