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You are here:Home » Antibodies » Abs to Enzymes, Methyltransferase » Anti -DNA Methyltransferase 3A (Dnmt 3A)

Anti -DNA Methyltransferase 3A (Dnmt 3A)

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Specifications

Clone Host Grade Applications
Polyclonal Chicken Affinity Purified E B
This protein is required for genome wide de novo methylation and is essential for development. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in the gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. This variant (1) represents the longest transcript and encodes the longest isoform.
Catalog #D3931-70B
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-1:2000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgY
HostChicken
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. No preservative added. Glycerol free.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa1-300
SpecificityRecognizes human DNA Methyltransferase 3A. Species Crossreactivity: Mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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