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You are here:Home » Antibodies » Abs to Enzymes, Polymerase » Anti -DNA Polymerase, beta (POLB)

Anti -DNA Polymerase, beta (POLB)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified IH
DNA polymerase beta is one of the four DNA-directed DNA-polymerases occuring in the nuclei of eukaryotic cells. It is a eukaryotic DNA polymerase primarily involved in gap-filling synthesis during base excision repair. It has unique ability to repair single-stranded DNA gaps smaller than 6 nucleotides and is the only eukaryotic DNA-polymerase able to fill small gaps. It is also responsible for adding new nucleotides to a growing chain by catalyzing a nucleotidyl transfer reaction. It is a single polypeptide chain of 335aa. It has no exonuclease (proofreading) activity.
Catalog #D3935-12B
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (formalin fixed paraffin embedded): 1:25-1:50
Optimal dilutions to be determined by the researcher.
Positive ControlTestis
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No11E173
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid, 0.05% sodium azide.
PurityPurified
ImmunogenDNA polymerase beta protein. Cellular Localization: Nuclear.
SpecificityRecognizes human DNA polymerase beta.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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